Acute Neuromuscular Adaptations in the Postural Control of Patients with Parkinson's Disease after Perturbed Walking.

摘要: Patients suffering from Parkinson’s disease (PD) present motor impairments reflected in the dynamics of center pressure (CoP) adjustments during quiet standing. One method to study CoP is entropic half-life (EnHL), which measures short-term correlations a time series at different scales. Changes EnHL suggest neuromuscular adaptations control posture. In this study, we sought investigate immediate changes patients with PD one session perturbed (experimental group) and unperturbed treadmill walking (control group). A total 39 participated study. The experimental group (n=19) walked on providing small tilting platform. (n=20) without perturbations. Each participant performed 5-minutes practice followed by three 5-minute training blocks or perturbation (with 3-minutes resting between). Quiet standing data was collected for 30 seconds pre-training, after each block, immediately post-training, 10 minutes retention. computed original surrogates (phase-randomized) signals medio-lateral (ML) anterior-posterior (AP) directions. Data analyzed using four-way mixed ANOVA. Increased values were observed both groups (Time effect, p < 0.001) as intervention progressed, suggesting surrogate significantly lower than (p 0.001), confirming that these come nonrandom processes. There no Group effect = 0.622), however analyzing significant Direction Time interaction 0.05), more pronounced ML direction observed. Altogether, our findings show decreases complexity adjustments, balance short period. Further investigations are required assess longer intervals.