Increased mortality and morbidity in mild primary hyperparathyroid patients

摘要: OBJECTIVE To describe mortality and disease-specific morbidities in patients with mild primary hyperparathyroidism (PHPT). DESIGN Retrospective population-based observational study. SETTING Tayside, Scotland, from 1997 to 2006. PARTICIPANTS Patients PHPT were selected a predefined cohort between MAIN OUTCOME MEASURES Standardised ratios (SMRs) examined for all-cause mortality, as well cardiovascular cancer mortality. morbidity standardised incidence also calculated eleven observed co-morbidities. RESULTS In total, there 1683 (69.1% female) identified Tayside. found have an increased risk of (SMR-all cause 2.62, 95% CI 2.39-2.86; SMR-cardiovascular 2.68, 2.34-3.05). had significantly developing cerebrovascular disease, renal dysfunction fractures compared the age- sex-adjusted general population. CONCLUSIONS Mortality untreated PHPT, which is similar more severe PHPT.