High Prevalence of Screen Detected Prostate Cancer in West Africans: Implications for Racial Disparity of Prostate Cancer

作者: Ann W. Hsing , Edward Yeboah , Richard Biritwum , Yao Tettey , Angelo M. De Marzo

DOI: 10.1016/J.JURO.2014.04.017

关键词:

摘要: Purpose: To our knowledge the reasons for high rates of prostate cancer in black American men are unknown. Genetic and lifestyle factors have been implicated. Better understanding in West African would help clarify why black such since groups share genetic ancestry yet different lifestyles screening practices. estimate burden we performed a population based study with biopsy confirmation Ghana.Materials Methods: We randomly selected 1,037 healthy 50 to 74 years old from Accra, Ghana specific antigen testing digital rectal examination. Men positive screen result (positive examination or greater than 2.5 ng/ml) underwent transrectal ultrasound guided biopsies.Results: Of 154 (14.9%) had 272 (26.2%) specif...

参考文章(32)
E. Steliarova-Foucher, M. Laversanne, J. Ferlay, D. Forman, S. Antoni, Freddie Ian Bray, C. Gombe Mbalawa, B. Kohler, M. Piñeros, D. H. Brewster, I. Soerjomataram, R. Swaminathan, Cancer Incidence in Five Continents ,(1997)
Garrett Hellenthal, George BJ Busby, Gavin Band, James F Wilson, Cristian Capelli, Daniel Falush, Simon Myers, None, A genetic atlas of human admixture history. Science. ,vol. 343, pp. 747- 751 ,(2014) , 10.1126/SCIENCE.1243518
SP Weinrich, MD Boyd, D Bradford, MS Mossa, M Weinrich, Recruitment of African Americans into prostate cancer screening. Cancer Practice. ,vol. 6, pp. 23- 30 ,(1998) , 10.1046/J.1523-5394.1998.1998006023.X
Jerome P. Richie, William J. Catalona, Frederick R. Ahmann, M'Liss A. Hudson, Peter T. Scardino, Robert C. Flanigan, Jean B. Dekernion, Timothy L. Ratliff, Louis R. Kavoussi, Bruce L. Dalkin, W.Bedford Waters, Michael T. MacFarlane, Paula C. Southwick, Effect of patient age on early detection of prostate cancer with serum prostate-specific antigen and digital rectal examination Urology. ,vol. 42, pp. 365- 374 ,(1993) , 10.1016/0090-4295(93)90359-I
M. L. Freedman, C. A. Haiman, N. Patterson, G. J. McDonald, A. Tandon, A. Waliszewska, K. Penney, R. G. Steen, K. Ardlie, E. M. John, I. Oakley-Girvan, A. S. Whittemore, K. A. Cooney, S. A. Ingles, D. Altshuler, B. E. Henderson, D. Reich, Admixture mapping identifies 8q24 as a prostate cancer risk locus in African-American men Proceedings of the National Academy of Sciences of the United States of America. ,vol. 103, pp. 14068- 14073 ,(2006) , 10.1073/PNAS.0605832103
Rosalind A Eeles, Ali Amin Al Olama, Sara Benlloch, Edward J Saunders, Daniel A Leongamornlert, Malgorzata Tymrakiewicz, Maya Ghoussaini, Craig Luccarini, Joe Dennis, Sarah Jugurnauth-Little, Tokhir Dadaev, David E Neal, Freddie C Hamdy, Jenny L Donovan, Ken Muir, Graham G Giles, Gianluca Severi, Fredrik Wiklund, Henrik Gronberg, Christopher A Haiman, Fredrick Schumacher, Brian E Henderson, Loic Le Marchand, Sara Lindstrom, Peter Kraft, David J Hunter, Susan Gapstur, Stephen J Chanock, Sonja I Berndt, Demetrius Albanes, Gerald Andriole, Johanna Schleutker, Maren Weischer, Federico Canzian, Elio Riboli, Tim J Key, Ruth C Travis, Daniele Campa, Sue A Ingles, Esther M John, Richard B Hayes, Paul DP Pharoah, Nora Pashayan, Kay-Tee Khaw, Janet L Stanford, Elaine A Ostrander, Lisa B Signorello, Stephen N Thibodeau, Dan Schaid, Christiane Maier, Walther Vogel, Adam S Kibel, Cezary Cybulski, Jan Lubinski, Lisa Cannon-Albright, Hermann Brenner, Jong Y Park, Radka Kaneva, Jyotsna Batra, Amanda B Spurdle, Judith A Clements, Manuel R Teixeira, Ed Dicks, Andrew Lee, Alison M Dunning, Caroline Baynes, Don Conroy, Melanie J Maranian, Shahana Ahmed, Koveela Govindasami, Michelle Guy, Rosemary A Wilkinson, Emma J Sawyer, Angela Morgan, David P Dearnaley, Alan Horwich, Robert A Huddart, Vincent S Khoo, Christopher C Parker, Nicholas J Van As, Christopher J Woodhouse, Alan Thompson, Tim Dudderidge, Chris Ogden, Colin S Cooper, Artitaya Lophatananon, Angela Cox, Melissa C Southey, John L Hopper, Dallas R English, Markus Aly, Jan Adolfsson, Jiangfeng Xu, Siqun L Zheng, Meredith Yeager, Rudolf Kaaks, W Ryan Diver, Mia M Gaudet, Mariana C Stern, Roman Corral, Amit D Joshi, Ahva Shahabi, Tiina Wahlfors, Teuvo LJ Tammela, Anssi Auvinen, Jarmo Virtamo, Peter Klarskov, Børge G Nordestgaard, M Andreas Røder, Sune F Nielsen, Stig E Bojesen, Afshan Siddiq, Liesel M FitzGerald, Suzanne Kolb, Erika M Kwon, Danielle M Karyadi, William J Blot, Wei Zheng, Qiuyin Cai, Shannon K McDonnell, Antje E Rinckleb, Bettina Drake, Graham Colditz, Dominika Wokolorczyk, Robert A Stephenson, Craig Teerlink, Heiko Muller, Dietrich Rothenbacher, Thomas A Sellers, Hui-Yi Lin, Chavdar Slavov, Vanio Mitev, Felicity Lose, Srilakshmi Srinivasan, Sofia Maia, Paula Paulo, Ethan Lange, Kathleen A Cooney, Antonis C Antoniou, Daniel Vincent, François Bacot, Daniel C Tessier, COGS–Cancer Research UK GWAS–ELLIPSE (part of GAME-ON) Initiative, Australian Prostate Cancer Bioresource, UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology, UK ProtecT (Prostate testing for cancer and Treatment) Study Collaborators, PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium, Zsofia Kote-Jarai, Douglas F Easton, None, Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array Nature Genetics. ,vol. 45, pp. 385- 391 ,(2013) , 10.1038/NG.2560
A P Chokkalingam, E D Yeboah, A DeMarzo, G Netto, K Yu, R B Biritwum, Y Tettey, A Adjei, S Jadallah, Y Li, L W Chu, D Chia, S Niwa, A Partin, I M Thompson, C Roehrborn, R N Hoover, A W Hsing, Prevalence of BPH and lower urinary tract symptoms in West Africans Prostate Cancer and Prostatic Diseases. ,vol. 15, pp. 170- 176 ,(2012) , 10.1038/PCAN.2011.43
Deborah S. Smith, Arnold D. Bullock, William J. Catalona, Jonathan D. Herschman, Racial differences in a prostate cancer screening study. The Journal of Urology. ,vol. 156, pp. 1366- 1369 ,(1996) , 10.1016/S0022-5347(01)65588-5
A. W. Hsing, S. S. Devesa, Trends and Patterns of Prostate Cancer: What Do They Suggest? Epidemiologic Reviews. ,vol. 23, pp. 3- 13 ,(2001) , 10.1093/OXFORDJOURNALS.EPIREV.A000792
Christopher A Haiman, Gary K Chen, William J Blot, Sara S Strom, Sonja I Berndt, Rick A Kittles, Benjamin A Rybicki, William B Isaacs, Sue A Ingles, Janet L Stanford, W Ryan Diver, John S Witte, Ann W Hsing, Barbara Nemesure, Timothy R Rebbeck, Kathleen A Cooney, Jianfeng Xu, Adam S Kibel, Jennifer J Hu, Esther M John, Serigne M Gueye, Stephen Watya, Lisa B Signorello, Richard B Hayes, Zhaoming Wang, Edward Yeboah, Yao Tettey, Qiuyin Cai, Suzanne Kolb, Elaine A Ostrander, Charnita Zeigler-Johnson, Yuko Yamamura, Christine Neslund-Dudas, Jennifer Haslag-Minoff, William Wu, Venetta Thomas, Glenn O Allen, Adam Murphy, Bao-Li Chang, S Lilly Zheng, M Cristina Leske, Suh-Yuh Wu, Anna M Ray, Anselm J M Hennis, Michael J Thun, John Carpten, Graham Casey, Erin N Carter, Edder R Duarte, Lucy Y Xia, Xin Sheng, Peggy Wan, Loreall C Pooler, Iona Cheng, Kristine R Monroe, Fredrick Schumacher, Loic Le Marchand, Laurence N Kolonel, Stephen J Chanock, David Van Den Berg, Daniel O Stram, Brian E Henderson, Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21 Nature Genetics. ,vol. 43, pp. 570- 573 ,(2011) , 10.1038/NG.839