Morphogenesis of the Pancreas of Bufo bufo during Metamorphosis

摘要: Histology and immunohistochemical reactivity (IR) toward insulin, glucagon, somatostatin14, pancreatic polypeptide were investigated in the pancreas other tissues of Bufo bufo during metamorphosis. Insulin IR cells appeared at very beginning metamorphosis among exocrine rich yolk platelets, not completely arranged acini. Less than 1 week later, also appeared. At metamorphic climax, both endocrine underwent extensive degeneration, mainly via apoptotic cellular death. this time number intensity reactions decreased for all hormones tested. Pancreatic reorganization began end climax.