Urinary tract infections at a Nigerian university hospital: Causes, patterns and antimicrobial susceptibility profile

摘要: Treatment of urinary tract infections (UTIs) is becoming difficult due to the increasing trend antibiotics resistance and this may necessitate an up date knowledge pattern. This study was therefore set ascertain bacterial patterns from UTIs at a University hospital. The retrospective in nature. Data generated urine cultures patients Calabar Teaching hospital for period five years (2004 2009) were compiled. Relevant information obtained age gender patients, organisms recovered their antibiotic susceptibility patterns. incidence UTI found be 7.7% (565/7,348) comprising 264 (46.7%) males 53.3% (301) females (P>0.05); 391 (69.2%) community acquired (CA) while 174 (30.8%) nosocomial (NC) origin. Infections significantly lower among those aged below 20 (P<0.05). commonest bacteria were Escherichia coli 18.6% (109), Klebsiella pneumoniae14.8% (87), Proteus species 13.1% (77) and Staphylococcus aureus 10.7% (63). Penicillin G, ampicillin, tetracycline, cloxacillin most inactive drugs ofloxacin, clavulanate + amoxycilline, ceftriaxone, colistin cefuroxime active with sensitivity CA isolates generally higher than NC ones. Rationality should applied prescription, consumptions prophylaxis. Hospitals adopt strict infection control methods; also use agricultural, veterinary pharmaceutical activities regulated order halt or reverse growing trend.   Key words: Antibiotics, infections, susceptibility, tract.