Abstract # 3135 Additive and interactive associations of optimism and depressive symptoms with inflammation: Findings from the DETECT study cohort

作者: S. Hulsken , S. Aldred , J.J. Veldhuijzen van Zanten , R. Herr , W. März

DOI: 10.1016/J.BBI.2018.11.256

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摘要: Dispositional optimism and depression have each been independently linked to inflammation. The current study investigated possible independent interactive (i.e. additive or moderating) associations with Analyses explored if such varied by health status. Plasma CRP, dispositional optimism, depressive symptoms were assessed in 5740 primary care patients, estimated using linear logistic regression. stratified type-2 diabetes, hypertension, coronary heart disease, adjusted for BMI, education, exercise, smoking, alcohol. Results the whole sample showed that had CRP (respectively β  = −.029,  = .029, all p  δ -  = .052, p

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