Developmental myosin heavy chain mRNA in masseter after orthognathic surgery: A preliminary study

作者: Khemais Oukhai , Nenad Maricic , Matthias Schneider , Winfried Harzer , Eve Tausche

DOI: 10.1016/J.JCMS.2010.06.001

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摘要: Abstract Introduction A microarray study showed an increase of developmental myosin heavy chain (MyHC) mRNA in the masseter muscle after surgery. The aim was to determine expression embryonic MYH3 and perinatal MYH8 for use as potential marker adaptation orthognathic Material methods 24 adult patients with a prognathic (11) or retrognathic (13) mandible were involved study. 192 biopsies taken from two parts muscles presurgically 6 months following. quantified using real-time polymerase reaction (RT-PCR). Absolute quantification done by CT-values. Results up-regulated prognathia (8.5, P Conclusion could play role functional surgery orofacial orthopaedics.

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