作者: Sankar Ghosh , Michael Karin
DOI: 10.1016/S0092-8674(02)00703-1
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摘要: The regulation of the transcription factor NF-kappaB activity occurs at several levels including controlled cytoplasmic-nuclear shuttling and modulation its transcriptional activity. A critical component in is IkappaB kinase (IKK) complex. This review focused on recent progress as well unanswered questions regarding function IKK.