Antitumor and antimetastatic actions of various natural products

摘要: Abstract Although it has been recently thought that a number of medicinal plants and foodstuffs have antitumor antimetastatic activities, the basis for this hearsay is unclear. Therefore, to clarify whether natural products preventive effects on tumors growth tumor metastasis, using some biochemical pharmacological approaches examine isolated from various food stuffs. In present review, actions compounds were clarified by analysis approaches. The such as Royal Jelly, tuna oil (main compound, DHA), EPA derivatives dimer low-molecular water-soluble chitosan inhibited and/or metastasis in liver or lung, through inhibition tumor-induced angiogenesis activation immune function. Chalcone xanthoangelol 4-hydroxyderricin Angelica keiskei roots also tumor-bearing mice, neovascularization stimulation functions. Moreover, pyroglutamate was Basidiomycete fungus Agaricus blazei an anti-angiogenic substance, lung mice.