Primary Liver Tumors Other than Hepatocellular Carcinoma: Clinical and Molecular Pearls

摘要: Liver tumors, excluding hepatocellular carcinoma and metastatic disease, are rare. However, it is important to understand how distinguish these lesions from carcinoma. They run the spectrum of benign malignant, some aggressive with relatively few therapeutic options. The goal this paper review most recent literature provide current insights into diagnosis, treatment, pathogenesis tumor types. Recent has focused on oncogenomics putative targets for intervention. Several ongoing studies elucidating molecular pathways evaluating novel therapies in rare tumors we focus findings, particularly intrahepatic cholangiocarcinoma fibrolamellar HCC. While advances promising, surgical resection continues be associated greatest survival benefit malignant liver. Clinicians must aware liver them develop a differential diagnosis complicated or atypical presentations. In understanding biology hold promise expanding diagnostic possibilities.