Rhodium-Catalyzed Ortho-Vinylation of 2-Arylpyridines and Its Application in the Total Synthesis of Palmatine
作者： Shan Lv , Ruifang Nie , Lingmei Guo , Yang Zheng , Yanzhao Liu
关键词:
摘要: An efficient protocol by Rh-catalyzed direct C–H vinylation of 2-arylpyridines with a commercially available and air-stable potassium vinyl donor has been developed. This method affords the corresponding pyridinyl styrene derivative moderate to excellent yields under mild conditions, which is extremely beneficial total synthesis natural product palmatine.
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