New method for the synthesis of difficultly available sterically hindered tritium-labeled pyridinium derivatives
作者： N. E. Shchepina , V. V. Avrorin , G. A. Badun , V. M. Fedoseev , S. B. Lewis
DOI: 10.1007/S10593-010-0544-8
关键词:
摘要: Direct phenylation of the nitrogen atom in pyridines was noted a study ion-molecule reactions free nucleogenic phenyl cations generated by β-decay tritium labeled benzene. A one-step synthesis unreported biologically active tritium-labeled N-phenyl-2,6-lutidinium and 2,4,6-collidi-nium salts. Steric factors, which significantly reduce yield case sym-collidine, play major role direct nitrogen.
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