Spray-dried dispersions and formulations of (s)-5-amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-(1,1,1-trifluoro propan-2-yl)-1h-pyrazole-4-carboxamide

作者: Stacey Renee Spencer , Barbara J. Brandhuber , Charles Todd Eary , Firas Khan , Vivian F. H. Renshaw

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摘要: A spray-dried dispersions and pharmaceutical composition of (S)-5-amino-3-(4-((5-fluoro-2- methoxybenzamido)methyl)phenyl)-1-(1,1,1-trifluoropropan-2-yl)-1H-pyrazole-4- carboxamide, pharmaceutically acceptable salts thereof, or a combination thereof the use dispersion in treatment cancer autoimmune inflammatory diseases are disclosed. Also provided crystalline forms (S)-5-amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-(1,1,1-trifluoropropan- 2-yl)-1H-pyrazole-4-carboxamide also useful diseases.

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