TL1A (TNFSF15) regulates the development of chronic colitis by modulating both T-helper 1 and T-helper 17 activation.
作者： Hidetoshi Takedatsu , Kathrin S. Michelsen , Bo Wei , Carol J. Landers , Lisa S. Thomas
DOI: 10.1053/J.GASTRO.2008.04.037
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摘要: … in chronic intestinal inflammation. Methods:We used dextran sodium sulfate (DSS)-induced chronic colitis … Next, we evaluated whether anti-TL1A treatment prevents the development of …
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John L. Prehn, Lisa S. Thomas, Carol J. Landers, Qi T. Yu, Kathrin S. Michelsen, Stephan R. Targan, The T Cell Costimulator TL1A Is Induced by FcγR Signaling in Human Monocytes and Dendritic Cells Journal of Immunology. ,vol. 178, pp. 4033- 4038 ,(2007) , 10.4049/JIMMUNOL.178.7.4033
L Birnbaumer, L Birnbaumer, C E Hörnquist, U Rudolph, U Rudolph, G R Harriman, X Lu, P M Rogers-Fani, S Shappell, G(alpha)i2-deficient mice with colitis exhibit a local increase in memory CD4+ T cells and proinflammatory Th1-type cytokines. Journal of Immunology. ,vol. 158, pp. 1068- 1077 ,(1997)
S. W. Binder, S. R. Targan, P. L. Mcallister, B. C. Sydora, M. Kronenberg, R. Aranda, Hui Ying Yang, Analysis of intestinal lymphocytes in mouse colitis mediated by transfer of CD4+, CD45RBhigh T cells to SCID recipients. Journal of Immunology. ,vol. 158, pp. 3464- 3473 ,(1997)
Levinus A. Dieleman, Ben U. Ridwan, Gary S. Tennyson, Kenneth W. Beagley, R.Patrick Bucy, Charles O. Elson, Dextran sulfate sodium-induced colitis occurs in severe combined immunodeficient mice Gastroenterology. ,vol. 107, pp. 1643- 1652 ,(1994) , 10.1016/0016-5085(94)90803-6
Konstantinos A. Papadakis, Daocheng Zhu, John L. Prehn, Carol Landers, Armine Avanesyan, Gina Lafkas, Stephan R. Targan, Dominant Role for TL1A/DR3 Pathway in IL-12 plus IL-18-Induced IFN-γ Production by Peripheral Blood and Mucosal CCR9+ T Lymphocytes The Journal of Immunology. ,vol. 174, pp. 4985- 4990 ,(2005) , 10.4049/JIMMUNOL.174.8.4985
Mitsunari Yamamoto, Kazuyuki Yoshizaki, Tadamitsu Kishimoto, Hiroaki Ito, IL-6 Is Required for the Development of Th1 Cell-Mediated Murine Colitis Journal of Immunology. ,vol. 164, pp. 4878- 4882 ,(2000) , 10.4049/JIMMUNOL.164.9.4878
Charles O. Elson, Yingzi Cong, Casey T. Weaver, Trenton R. Schoeb, Terrill K. McClanahan, Robert B. Fick, Robert A. Kastelein, Monoclonal anti-interleukin 23 reverses active colitis in a T cell-mediated model in mice. Gastroenterology. ,vol. 132, pp. 2359- 2370 ,(2007) , 10.1053/J.GASTRO.2007.03.104
B. Wei, P. Velazquez, O. Turovskaya, K. Spricher, R. Aranda, M. Kronenberg, L. Birnbaumer, J. Braun, Mesenteric B cells centrally inhibit CD4+ T cell colitis through interaction with regulatory T cell subsets. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 102, pp. 2010- 2015 ,(2005) , 10.1073/PNAS.0409449102
Ivan J Fuss, Christoph Becker, Zhiqiong Yang, Catherine Groden, Ronald L Hornung, Frank Heller, Markus F Neurath, Warren Strober, Peter J Mannon, Both IL‐12p70 and IL‐23 are synthesized during active Crohn's disease and are down‐regulated by treatment with anti‐IL‐12 p40 monoclonal antibody Inflammatory Bowel Diseases. ,vol. 12, pp. 9- 15 ,(2006) , 10.1097/01.MIB.0000194183.92671.B6
Charles O. Elson, Yingzi Cong, Vance J. McCracken, Reed A. Dimmitt, Robin G. Lorenz, Casey T. Weaver, Experimental Models of Inflammatory Bowel Disease Reveal Innate, Adaptive, and Regulatory Mechanisms of Host Dialogue With the Microbiota Immunological Reviews. ,vol. 206, pp. 260- 276 ,(2005) , 10.1111/J.0105-2896.2005.00291.X