Phase II randomized trial of bortezomib (B) plus irinotecan (I) or B with addition of I at progression in recurrent (R) or metastatic (M) squamous cell carcinoma of the head and neck (SCCHN) (E1304): A trial of the Eastern Cooperative Oncology Group

作者: J. Gilbert , J. Lee , A. Argiris , L. Feldman , M. Haigentz

DOI: 10.1200/JCO.2009.27.15_SUPPL.6020

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摘要: 6020 Background: B, inhibits activation of NF- κβ and growth SCCHN cell lines. NF-κβ dysregulation contributes to chemoresistance, including I. Pretreatment with B increases tumor sensi...

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