Multiplex Immunoassay of Lower Genital Tract Mucosal Fluid from Women Attending an Urban STD Clinic Shows Broadly Increased IL1ß and Lactoferrin
作者： Gregory T. Spear , Sabrina R. Kendrick , Hua Y. Chen , Tin T. Thomas , Mieoak Bahk
DOI: 10.1371/JOURNAL.PONE.0019560
关键词:
摘要: Background More than one million new cases of sexually transmitted diseases (STDs) occur each day. The immune responses and inflammation induced by STDs other frequent non-STD microbial colonizations (i.e. Candida bacterial vaginosis) can have serious pathologic consequences in women including adverse pregnancy outcomes, infertility increased susceptibility to infection pathogens. Understanding the types mediators that are elicited lower genital tract these infections/colonizations give important insights into innate adaptive pathways activated lead strategies for preventing effects.
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