Ligustilide inhibits microglia-mediated proinflammatory cytokines production and inflammatory pain.

作者: Ming-Di Zhu , Lin-Xia Zhao , Xiao-Tian Wang , Yong-Jing Gao , Zhi-Jun Zhang

DOI: 10.1016/J.BRAINRESBULL.2014.10.002

关键词:

摘要: … of complete Freund's adjuvant (CFA)-induced mechanical allodynia and thermal hyperalgesia. … One microgram of total RNA was converted to cDNA by using reverse transcription kit (…

参考文章(56)
Xiao-mei Wu, Zhong-ming Qian, Li Zhu, Fang Du, Wing-ho Yung, Qi Gong, Ya Ke, Neuroprotective effect of ligustilide against ischaemia-reperfusion injury via up-regulation of erythropoietin and down-regulation of RTP801. British Journal of Pharmacology. ,vol. 164, pp. 332- 343 ,(2011) , 10.1111/J.1476-5381.2011.01337.X
Christian König, Maxim Zharsky, Christian Möller, Hans-Georg Schaible, Andrea Ebersberger, Involvement of peripheral and spinal tumor necrosis factor α in spinal cord hyperexcitability during knee joint inflammation in rats. Arthritis & Rheumatism. ,vol. 66, pp. 599- 609 ,(2014) , 10.1002/ART.38271
Edgar Alfonso Romero-Sandoval, Joyce A DeLeo, Ryan J Horvath, Neuroimmune interactions and pain: focus on glial-modulating targets. Current opinion in investigational drugs. ,vol. 9, pp. 726- 734 ,(2008)
Tarek A. Samad, Kimberly A. Moore, Adam Sapirstein, Sara Billet, Andrew Allchorne, Stephen Poole, Joseph V. Bonventre, Clifford J. Woolf, Interleukin-1β-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity Nature. ,vol. 410, pp. 471- 475 ,(2001) , 10.1038/35068566
Yong-Jing Gao, Zhen-Zhong Xu, Yen-Chin Liu, Yeong-Ray Wen, Isabelle Decosterd, Ru-Rong Ji, The c-Jun N-terminal kinase 1 (JNK1) in spinal astrocytes is required for the maintenance of bilateral mechanical allodynia under a persistent inflammatory pain condition Pain. ,vol. 148, pp. 309- 319 ,(2010) , 10.1016/J.PAIN.2009.11.017
Kui J. Zhao, Tina T. X. Dong, Peng F. Tu, Zong H. Song, Chun K. Lo, Karl W. K. Tsim, Molecular genetic and chemical assessment of radix Angelica (Danggui) in China. Journal of Agricultural and Food Chemistry. ,vol. 51, pp. 2576- 2583 ,(2003) , 10.1021/JF026178H
Ling Zhang, Temugin Berta, Zhen-Zhong Xu, Tong Liu, Jong Yeon Park, Ru-Rong Ji, TNF-alpha contributes to spinal cord synaptic plasticity and inflammatory pain: Distinct role of TNF receptor subtypes 1 and 2 Pain. ,vol. 152, pp. 419- 427 ,(2011) , 10.1016/J.PAIN.2010.11.014
Terry C.T. Or, Cindy L.H. Yang, Anna H.Y. Law, James C.B. Li, Allan S.Y. Lau, Isolation and identification of anti-inflammatory constituents from Ligusticum chuanxiong and their underlying mechanisms of action on microglia Neuropharmacology. ,vol. 60, pp. 823- 831 ,(2011) , 10.1016/J.NEUROPHARM.2010.12.002