摘要: Whole body screening with computed tomography is the focus of a major advertising campaign in United States. Enticing testimonials on billboards and radio spots urge public to use this technology, implying that there much gain little lose. How should primary care doctors advise their patients? In one sense has offer. As part study conducted by National Institutes Health, our centre used screen for lung cancer past four years identified 56 cancers. Fully 62% non-small cell cancers were stage IA.1 In absence screening, only 15-20% present at IA. Five year survival I cancers, which about 60-70%, higher than diagnosed more advanced stages. There doubt sensitive chest x ray detecting small, early We found two measuring 3 mm diameter. Recognising we patients cancer, could ask why …
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Takashi Chishima, A. R. Moossa, Hiroshi Shimada, Robert M. Hoffman, Meng Yang, Ping Jiang, Yuying Tan, Xiaoen Wang, Satoshi Hasegawa, Widespread skeletal metastatic potential of human lung cancer revealed by green fluorescent protein expression. Cancer Research. ,vol. 58, pp. 4217- 4221 ,(1998)
Alain Bernard, Hani Shennib, Resection of pulmonary nodules using video-assisted thoracic surgery The Annals of Thoracic Surgery. ,vol. 61, pp. 202- 205 ,(1996) , 10.1016/0003-4975(95)01014-9
Patrick S. Romano, David H. Mark, Patient and Hospital Characteristics Related to In-Hospital Mortality after Lung Cancer Resection* Chest. ,vol. 101, pp. 1332- 1337 ,(1992) , 10.1378/CHEST.101.5.1332
Janusz W Rak, Bradley D St Croix, Robert S Kerbel, Consequences of angiogenesis for tumor progression, metastasis and cancer therapy. Anti-Cancer Drugs. ,vol. 6, pp. 3- 18 ,(1995) , 10.1097/00001813-199502000-00001
Parthiv J. Mahadevia, Lee A. Fleisher, Kevin D. Frick, John Eng, Steven N. Goodman, Neil R. Powe, Lung Cancer Screening With Helical Computed Tomography in Older Adult Smokers: A Decision and Cost-effectiveness Analysis JAMA. ,vol. 289, pp. 313- 322 ,(2003) , 10.1001/JAMA.289.3.313
Michael J. Mack, Stephen R. Hazelrigg, Rodney J. Landreneau, Tea E. Acuff, Thoracoscopy for the diagnosis of the indeterminate solitary pulmonary nodule The Annals of Thoracic Surgery. ,vol. 56, pp. 825- 832 ,(1993) , 10.1016/0003-4975(93)90339-J
Stephen J. Swensen, James R. Jett, Thomas E. Hartman, David E. Midthun, Jeff A. Sloan, Anne-Marie Sykes, Gregory L. Aughenbaugh, Medy A. Clemens, Lung Cancer Screening With CT: Mayo Clinic Experience Radiology. ,vol. 226, pp. 756- 761 ,(2003) , 10.1148/RADIOL.2263020036
Shusuke Sone, Shodayu Takashima, Feng Li, Zhigang Yang, Takayuki Honda, Yuichiro Maruyama, Minoru Hasegawa, Takeshi Yamanda, Keishi Kubo, Kazuhisa Hanamura, Kazuhiro Asakura, Mass screening for lung cancer with mobile spiral computed tomography scanner The Lancet. ,vol. 351, pp. 1242- 1245 ,(1998) , 10.1016/S0140-6736(97)08229-9
Gerald M. Saidel, Lance Allen Liotta, Jerome Kleinerman, Quantitative relationships of intravascular tumor cells, tumor vessels and pulmonary metastases following tumor implantation. Cancer Research. ,vol. 34, pp. 997- 1004 ,(1974)
Judah Folkman, Clinical Applications of Research on Angiogenesis New England Journal of Medicine. ,vol. 333, pp. 1757- 1763 ,(1995) , 10.1056/NEJM199512283332608