Does chemotherapy increase the risk of respiratory complications after pneumonectomy

摘要: Objective The impact of induction chemotherapy on postoperative complications after pneumonectomy remains unclear. aim the study was to test hypothesis that may increase risk respiratory complications. Methods Data from 202 consecutive standard pneumonectomies performed for lung cancer were collected and analyzed. Postoperative 90-day mortality, overall morbidity, complication rates evaluated in patients who had no treatment (group A, n = 103) as well those received it (n 99, group B). Preoperative inserted a variable together with 12 other variables (age, sex, smoking status, body mass index, previous cardiac event, American Society Anesthesiologists score, preoperative forced expiratory volume 1 second [percent], diffusion capacity carbon monoxide adjusted alveolar side pneumonectomy, perfusion removed lung, operating time, blood transfusion) into univariate multivariate logistic regression. Results No difference terms mortality recorded between A (4.9%) B (3%, P > .05). Respiratory more frequent than (19 cases, 19.2%, vs 7 6.8%, .008). Univariate regression has demonstrated pulmonary over age 70 aged or less (25.7% 10.2, .02), lower (18.3% 5.95%, .06), (19.2% 6.8, Logistic confirmed role (odds ratio 6.3), 4.4), 0.33) factors Conclusions Standard is safe procedure even chemotherapy, rate order 5%, but this increases years. In case significantly increased, apparently not affecting rate.