Carcinoma of the colon and rectum:The natural history reviewed in 1704 patients

作者: Burton Eisenberg , Jerome J. Decosse , Frank Harford , Joel Michalek

DOI: 10.1002/1097-0142(19820315)49:6<1131::AID-CNCR2820490611>3.0.CO;2-T

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摘要: For 1704 patients with large bowel cancer compiled by the Armed Forces Central Medical Registry, selected prognostic factors were related to five-year or longer survival. The majority of late deaths (those occurring after five years) resulted from in descending colon, sigmoid colon rectum rather than right transverse colon. example, among all rectum, 15.4% those Dukes' B tumors and 10.9% C died rectal between ten years diagnosis. When survival rates compared, (8 deaths/93 at risk) fared significantly better left (33 deaths/171 risk; P = 0.01). Among left-sided carcinoma, a further significant difference was found when stage disease considered: A cancers (3 deaths/47 risk (21 deaths/74 (P 0.002). stages disease, worse lesions 60 months. Of who years, 69% had recurrence months, most recurrences located rectum. These results show differences respect both site initial disease. Our findings indicate that many have slowly progressive natural history.

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