Suppression of Central Sleep Apnea by Continuous Positive Airway Pressure and Transplant-Free Survival in Heart Failure A Post Hoc Analysis of the Canadian Continuous Positive Airway Pressure for Patients With Central Sleep Apnea and Heart Failure Trial (CANPAP)
作者： Michael Arzt , John S. Floras , Alexander G. Logan , R. John Kimoff , Frederic Series
DOI: 10.1161/CIRCULATIONAHA.106.683482
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摘要: Background— In the main analysis of Canadian Continuous Positive Airway Pressure (CPAP) for Patients with Central Sleep Apnea (CSA) and Heart Failure Trial (CANPAP), CPAP had no effect on heart transplant–free survival; however, only reduced mean apnea-hypopnea index to 19 events per hour sleep, which remained above trial inclusion threshold 15. This stratified CANPAP tested hypothesis that suppression CSA below this by would improve left ventricular ejection fraction survival. Methods Results— Of 258 failure patients in CANPAP, 110 130 randomized control group 100 128 sleep studies 3 months later. were divided post hoc into those whose was or not 15 at time (CPAP-CSA suppressed, n=57, CPAP-CSA unsuppressed, n=43, respectively). Their changes tra...
sci-hub.se 参考文章(28)
Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF) The Lancet. ,vol. 353, pp. 2001- 2007 ,(1999) , 10.1016/S0140-6736(99)04440-2
Harris Cd, Bonekat Hw, Staats Ba, Offord Kp, Chest wall motion in sleep apnea. The American review of respiratory disease. ,vol. 130, pp. 59- 63 ,(1984) , 10.1164/ARRD.1984.130.1.59
Richard S. T. Leung, Tung M. Diep, Michael E. Bowman, Geraldo Lorenzi-Filho, T. Douglas Bradley, Provocation of Ventricular Ectopy by Cheyne-Stokes Respiration in Patients with Heart Failure Sleep. ,vol. 27, pp. 1337- 1343 ,(2004) , 10.1093/SLEEP/27.7.1337
HELMUT TESCHLER, JENS DÖHRING, YOU-MING WANG, MICHAEL BERTHON-JONES, Adaptive pressure support servo-ventilation: a novel treatment for Cheyne-Stokes respiration in heart failure American Journal of Respiratory and Critical Care Medicine. ,vol. 164, pp. 614- 619 ,(2001) , 10.1164/AJRCCM.164.4.9908114
Don D. Sin, Alexander G. Logan, Fabia S. Fitzgerald, Peter P. Liu, T. Douglas Bradley, Effects of Continuous Positive Airway Pressure on Cardiovascular Outcomes in Heart Failure Patients With and Without Cheyne-Stokes Respiration Circulation. ,vol. 102, pp. 61- 66 ,(2000) , 10.1161/01.CIR.102.1.61
DON D. SIN, FABIA FITZGERALD, JOHN D. PARKER, GARY NEWTON, JOHN S. FLORAS, T. DOUGLAS BRADLEY, Risk Factors for Central and Obstructive Sleep Apnea in 450 Men And Women with Congestive Heart Failure American Journal of Respiratory and Critical Care Medicine. ,vol. 160, pp. 1101- 1106 ,(1999) , 10.1164/AJRCCM.160.4.9903020
Jonathan D. Sackner-Bernstein, Marcin Kowalski, Marshal Fox, Keith Aaronson, Short-term Risk of Death After Treatment With Nesiritide for Decompensated Heart Failure A Pooled Analysis of Randomized Controlled Trials JAMA. ,vol. 293, pp. 1900- 1905 ,(2005) , 10.1001/JAMA.293.15.1900
M T Naughton, P P Liu, D C Bernard, R S Goldstein, T D Bradley, Treatment of Congestive Heart Failure and Cheyne-Stokes Respiration During Sleep by Continuous Positive Airway Pressure American Journal of Respiratory and Critical Care Medicine. ,vol. 151, pp. 92- 97 ,(1995) , 10.1164/AJRCCM.151.1.7812579
Michael Arzt, Martina Schulz, Roland Wensel, Sylvia Montalvaèn, Friedrich C Blumberg, Guünter A.J Riegger, Michael Pfeifer, Nocturnal continuous positive airway pressure improves ventilatory efficiency during exercise in patients with chronic heart failure. Chest. ,vol. 127, pp. 794- 802 ,(2005) , 10.1378/CHEST.127.3.794
T. Douglas Bradley, Richard M. Holloway, Peter R. McLaughlin, Bette L. Ross, Janice Walters, Peter P. Liu, Cardiac output response to continuous positive airway pressure in congestive heart failure The American review of respiratory disease. ,vol. 145, pp. 377- 382 ,(1992) , 10.1164/AJRCCM/145.2_PT_1.377