作者: Yao Xia , Sun Xiuyun , Rao Yu
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摘要: The invention relates to a micromolecular reversible BTK inhibitor for treating rheumatoid arthritis, and specifically provides compound. compound is the as shown in formula I, or stereisomer, geometrical isomer tautomer thereof, nitric oxide, aquo-complex, solvate, metabolite pharmaceutically acceptable salts prodrugs. inventor finds that polysubstitutedquinolone derivate thereof I can be used high activity during arthritis.