Preoperative total parenteral nutrition (TPN) in severe Crohn's disease.

摘要: This study was performed to evaluate the effect of preoperative total parenteral nutrition (TPN) on results after surgical treatment patients with severe Crohn's disease. Of 67 admitted complications disease, 51 had active disease and abdominal masses, fistulas and/or obstruction (mean activity index score, 301). Forty-four received TPN for a mean period 33 days. Complications were limited. Spontaneous closure achieved in 75% cases. Serum albumin levels improved significantly, from 29.1 +/- 1.1 gm/L 35.4 0.7 (p less than 0.001). Mean body weights 81% 89% ideal or 52.6 kg 57.2 kg, respectively 0.05). Surgical procedures facilitated by remission inflammatory process associated major rate only 6%. No deaths occurred. hospital stay TPN-treated group 63 is an effective complicated The prolonged high costs, however, are disadvantages this approach. Preoperative should therefore be limited