A Two-Magnet System to Push Therapeutic Nanoparticles

摘要: Magnetic fields can be used to direct magnetically susceptible nanoparticles disease locations: infections, blood clots, or tumors. Any single magnet always attracts (pulls) ferro- para-magnetic particles towards it. External magnets have been pull therapeutics into tumors near the skin in animals and human clinical trials. Implanting magnetic materials patients (a feasible approach some cases) has envisioned as a means of reaching deeper targets. Yet there are number needs, ranging from treatments inner ear, antibiotic-resistant infections cardiac arrhythmias, which would benefit an ability "inject", push in, nanomedicines. We develop, analyze, experimentally demonstrate novel, simple, effective arrangement just two permanent that particles. Such system might treat diseases ear; intravenously injected orally administered cannot reach due blood-brain barrier.