摘要: The main areas that are reviewed in this chapter include constipation, diarrhea, irritable bowel syndrome, inflammatory disease (ulcerative colitis and Crohn’s disease), colorectal cancer. Constipation may also be a side effect of medication intake, particular, antidepressants, antihistamines, opioids, diuretics. Diarrhea can acute (less than 14 days duration usually caused by enteric infections), persistent (lasting more days), or chronic 30 more). Antibiotic-associated diarrhea (AAD) occurs 2 to 8 weeks after treatment with antibiotics, especially broad-spectrum antimicrobial agents. Only one study the prebiotics consumption on prevention traveler’s has been published. In study, 244 healthy subjects who were traveling destinations at high medium risk for randomized groups receiving either fructo-oligosaccharides (FOS) (10 g/day) placebo orally prior during 2-week excursion. Irritable syndrome (IBS) is very common gastrointestinal disorder associated wide range symptoms, including abdominal pain discomfort, loose hard stools, bloating, flatulence. Generally, IBS focused medications rather nutritional approaches. decline immune function mainly changes T-cell populations, although other components system affected. Clinical studies applications human medicine limited compared numbers reports regarding probiotics.