作者: Menachem Rottem , Yehuda Shoenfeld
DOI: 10.1097/01.MOO.0000122312.13359.EB
关键词:
摘要: Purpose of review Vaccines have had a major effect on controlling the spread infectious diseases, but use certain vaccines was linked to potential allergic and autoimmune side effects in healthy often high-risk populations. In this authors summarize current knowledge such risks. Recent findings Immediate systemic reactions after vaccination with commonly used are extremely rare. Use The data risk associated important including influenza, smallpox, pneumococcus, Japanese encephalitis, Bacille Calmette-Guerin, pertussis, measles, mumps, rubella. Two main components were identified as source for vaccines: gelatin egg protein. There is growing interest interactions between infant development atopic disease. addition, there concern that genetic atopy influences capacity respond during infancy. no evidence Calmette-Guerin; pertussis; influenza; rubella; or smallpox an later life. Immunotherapy provides efficacious safe method treatment conditions by immunomodulation immune system. possibility triggering unmasking autoimmunity genetically susceptible individuals cannot be ruled out, general population risk-to-benefit ratio overwhelmingly favor vaccinations. Summary Childhood remains essential part child health programs should not withheld, even from children predisposed allergy. Vaccinations safe, special attention taken anaphylactic foods, patients diseases.