Impact of serum albumin levels on long-term outcomes in patients undergoing percutaneous coronary intervention.

摘要: Epidemiological studies have demonstrated an association between low serum albumin levels and both coronary artery disease (CAD) mortality. However, the long-term clinical impact of level in patients with CAD undergoing percutaneous intervention (PCI) has not yet been fully investigated. We studied 2860 all-comer who underwent their first PCI had data available for pre-procedural 2000 2011. Patients were assigned to tertiles based on levels. evaluated incidence major adverse cardiac events (MACE), including all-cause death nonfatal myocardial infarction. Mean was 4.0 ± 0.5 g/dL. Lower associated older age, lower body mass index (BMI), higher prevalences female sex, ACS chronic kidney (CKD). During median follow-up period 7.4 years, Kaplan–Meier curves showed ongoing divergence rates MACE among (albumin 4.1 g/dl: 22.9%; log-rank p < 0.0001). After adjusting established cardiovascular risk factors acute syndrome, BMI CKD, significantly (HR 1.74 per 1-g/dl decrease, 95% CI 1.34–2.26, p < 0.0001) mortality 1.74, 1.30–2.33, p = 0.0002). Pre-PCI worse outcomes, independent traditional factors. Assessing may allow stratification PCI.