Coated surfaces for immobilizing negatively charged anticoagulating agents from blood fluid

摘要: A wound closure apparatus is provided which utilizes blood fluid by activating the clotting cascade of outside body within a substantially enclosed sterile container then introducing, to site complete clotting. An for providing ways inhibiting anticoagulating agents, and slowing fibrin clot degradation are also disclosed. Kits practicing invention singularly or in combination with, and/or associated with preferred procedures The provides initiation ( 1 ) including containment chamber an aliquot fluid, either autologous from donor sources can be received, retained. In embodiments, further includes heparin binding agent will bind remove it fluid. include procoagulating agent, wherein initiated when accepted into chamber.