Asymptotic Properties of the Sequential Empirical ROC and PPV Curves
作者： Ziding Feng , Joseph S. Koopmeiners
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摘要: The receiver operating characteristic (ROC) curve, the positive predictive value (PPV) curve and negative (NPV) are three common measures of performance for a diagnostic biomarker. independent increments covariance structure assumption is in group sequential study design literature. Showing that summary ROC, PPV NPV curves have an will provide theoretical foundation designing biomarker studies. often estimated empirically to avoid assumptions about distributional form biomarkers. In this paper we derive asymptotic theory empirical curves. These results used show holds some when empirically. Hosted by Berkeley Electronic Press
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