ANTIFUNGAL ACTIVITIES OF ORIGANUM VULGARE SUBSP. HIRTUM, MENTHA SPICATA, LAVANDULA ANGUSTIFOLIA AND SALVIA FRUTICOSA ESSENTIAL OILS AGAINST HUMAN PATHOGENIC FUNGI
作者： Konstantia Adam , Afroditi Sivropoulou , Stella Kokkini , Thomas Lanaras , Minas Arsenakis
DOI: 10.1021/JF9708296
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摘要: The essential oils of Origanum vulgare subsp. hirtum, Mentha spicata, Lavandula angustifolia, and Salvia fruticosa exhibited antifungal properties against the human pathogens Malassezia furfur, Trichophyton rubrum, Trichosporon beigelii. Of four oils, O. hirtum oil showed highest fungicidal activity at a dilution 1/50000 caused 95% reduction in number metabolically active cells within 6 h exposure. Among main components carvacrol thymol levels activity. therapeutic efficacy was tested rats experimentally infected with T. rubrum yielded promising results. Furthermore, above were Ames test did not exhibit any mutagenic
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