Palliative resection of the primary tumour in stage IV rectal cancer

摘要: Aim  The aim of this study was to investigate the use resection in a cohort palliatively treated patients with stage IV rectal cancer. To avoid selection bias, particular attention paid correction for comorbidity and extent disease. Method  Patients cancer two hospitals Groningen were consecutively included over 5-year period. Comorbidity defined as major (dementia, cardiac failure or left ventricle ejection fraction < 30%, severe chronic obstructive pulmonary disease), minor (diabetes, hypertension, mild renal disease disease) none. effect patient characteristics on survival assessed using Kaplan–Meier Cox regression analyses. Results  Of 88 patients, 11 (13%) underwent elective surgical without chemotherapy, 15 (17%) received both 21 (24%) palliative chemotherapy only 41 (47%) had supportive care only. (P 0.01), hospital = 0.02) 0.04) correlated worse survival. surgically survived longer than nonsurgically, when data corrected age, comorbidity, [hazard ratio (HR) 0.4 (95% CI 0.2–0.7)]. Perioperative morbidity seen 38% 30-day mortality 0%. Conclusion  In retrospective cohort, associated independently distant metastases, age comorbidity.