The Role of Zinc in Candida Dimorphism

摘要: The yeast Candida albicans remains a persistent pathogen in humans (42). For reasons that still remain obscure, this commensal is able to sense changes the physiology of host, especially debilitating ones, and attack opportunistically tissues ranging diversity from vaginal epithelium heart valve (2, 3, 4, 42, 45). species are capable growing at least two distinct forms: “yeast” or budding form elongate mycelial Both found infected tissue both may play role invasion process. Several mycelium-minus mutants have been be relatively nonvirulent (Buckley, personal communication), supporting suggestion mycelium invades tissue.