Infertility in women with pemphigus vulgaris and other autoimmune diseases

摘要: Background: Pemphigus vulgaris (PV) is an autoimmune disease. Autoimmune diseases may adversely affect reproductive function and could result in infertility. Objective: Our purpose was to describe nine young women with PV Methods: A retrospective study performed. Clinical characteristics, immunopathologic features, treatment, clinical course, long-term follow-up were determined. Results: Eight of patients unable become pregnant. One patient became pregnant during a period remission. In eight the patients, cause infertility ovarian. Anti-sperm antibodies present two patients. Conclusion: Some have No definitive conclusion about frequency these or its relation can be drawn. However, observations indirectly demonstrate that there important interactions between immune hormonal systems.