Proteomic Approaches for Biomarker Panels in Cancer.
作者： Cristiana Tanase , Radu Albulescu , Monica Neagu
DOI: 10.1080/15321819.2015.1116009
关键词:
摘要: Proteomic technologies remain the main backbone of biomarkers discovery in cancer. The continuous development proteomic also enlarges bioinformatics domain, thus founding pillars cancer therapy. source for diagnostic/prognostic/therapy monitoring biomarker panels are molecules that have a dual role, being both indicators disease and therapy targets. technologies, such as mass-spectrometry approaches protein array represent can depict these biomarkers. Herein, we will illustrate some most recent strategies cancer, including immune-markers use stem cells target challenges need new forms cross-disciplinary conglomerates result increased tailored access to treatments patients; diagnostic companies would benefit from enhanced co-development companion diagnostics pharmaceutical companies. In technology optimization biomarkers, immune assays leaders machinery.
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