Development of an AC electrokinetics-based immunoassay system for on-site serodiagnosis of infectious diseases

摘要: Abstract This paper presents a lab-chip immunoassay system that is based on AC electrothermal effect. It uses poly (dimethylsiloxane) microfluidic cartridge as the disposable immunoreactor, which key processes such reagent delivery, incubation and washing are performed using low voltage signals. A cost, reconfigurable detection module constructed light emitting diode induced fluorescence. Along with employed effect, developed diagnostic has demonstrated much shorter time than conventional pressure driven flow system. tenfold acceleration in achieved while safely differentiating between positive negative primary antibodies large margin. Other merits of this include portability, rapid consumption.