Antifertility Effect of Ethanolic Extract of Juniperus phoenica (L.) in Male Albino Rats
作者： Hanada G. Shkukani , Abdulazim S. Salhab , Ahmad M. Disi , Maha S. Shomaf , Farouk Al Quadan
DOI: 10.1080/15228940802152463
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摘要: The plant Juniperus phoenica (L.) (Cupressaceae) is widely growing on the rocky soils of Mediterranean regions. In Jordan, distributed in different locations and used as a folk medicine to treat rheumatism, edema, urinary tract diseases. This study aimed investigate antifertility effect J. male albino rats. Animals were administered single daily intraperitoneal injections 400 or 800 mg/kg cones ethanol extract vehicle (dimethyl sulfoxide) for 21 consecutive days. A marked dose-dependent decrease counts motility sperms collected from cauda epididymis treated rats was observed compared with control. Furthermore, pregnancy rate females markedly reduced by 60% 80% after mating males mg/kg, respectively. At same time, significant decreases detected seminal vesicles testicular weight that received control Testosterone levels decreased significantly both groups Histologically, seminiferous tubules showed arrests spermatogenesis number mature sperms. Therefore, results this suggest ethanolic possesses potential effects.
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