Rate of Change in Serum Prostate Specific Antigen Levels as a Method For Prostate Cancer Detection
作者： Deborah S. Smith , William J. Catalona
DOI: 10.1016/S0022-5347(17)32528-4
关键词:
摘要: To examine prospectively the usefulness of measurement rate change in serum prostate specific antigen levels (PSA slope) detecting cancer a PSA-based screening study, we evaluated 982 serially screened men whose initial was negative for cancer. All had at least 1 PSA value greater than 4.0 ng./ml. and all ultimately underwent prostatic biopsy. For those who entered study with normal levels, slope cutoff point 0.75 per year or more maximized sensitivity specificity predicting (odds ratio 7.20, 95% confidence interval 4.52 to 11.47). This most predictive 70 years old younger. elevated (greater ng./ml.) lower (0.4 more) 2.73, 1.82 4.07). We conclude that is useful serial screening, although its varies patient age level.
elsevier.com
jurology.com 参考文章(10)
David W. Keetch, William J. Catalona, Deborah S. Smith, Serial prostatic biopsies in men with persistently elevated serum prostate specific antigen values The Journal of Urology. ,vol. 151, pp. 1571- 1574 ,(1994) , 10.1016/S0022-5347(17)35304-1
Stanley Lemeshow, David W. Hosmer, Applied Logistic Regression ,(1989)
Sue Thiemann, Helena Chmura Kraemer, A strategy to use soft data effectively in randomized controlled clinical trials. Journal of Consulting and Clinical Psychology. ,vol. 57, pp. 148- 154 ,(1989) , 10.1037//0022-006X.57.1.148
William J Catalona, Deborah S Smith, Timothy L Ratliff, Joseph W Basler, Detection of Organ-Confined Prostate Cancer Is Increased Through Prostate-Specific Antigen—Based Screening JAMA: The Journal of the American Medical Association. ,vol. 270, pp. 948- 954 ,(1993) , 10.1001/JAMA.1993.03510080052031
Joseph E. Oesterling, David C. Rice, William J. Glenski, Erik J. Bergstralh, Effect of cystoscopy, prostate biopsy, and transurethral resection of prostate on serum prostate-specific antigen concentration Urology. ,vol. 42, pp. 276- 282 ,(1993) , 10.1016/0090-4295(93)90616-I
H Ballentine Carter, Jay D Pearson, E Jeffrey Metter, Larry J Brant, Daniel W Chan, Reubin Andres, James L Fozard, Patrick C Walsh, Longitudinal evaluation of prostate-specific antigen levels in men with and without prostate disease. JAMA. ,vol. 267, pp. 2215- 2220 ,(1992) , 10.1001/JAMA.1992.03480160073037
Jerry J.J. Yuan, Douglas E. Coplen, John A. Petros, Robert S. Figenshau, Timothy L. Ratliff, Deborah S. Smith, William J. Catalona, Effects of Rectal Examination, Prostatic Massage, Ultrasonography and Needle Biopsy on Serum Prostate Specific Antigen Levels The Journal of Urology. ,vol. 147, pp. 810- 814 ,(1992) , 10.1016/S0022-5347(17)37392-5
William J. Catalona, Deborah S. Smith, Timothy L. Ratliff, Kathy M. Dodds, Douglas E. Coplen, Jerry J.J. Yuan, John A. Petros, Gerald L. Andriole, Measurement of Prostate-Specific Antigen in Serum as a Screening Test for Prostate Cancer New England Journal of Medicine. ,vol. 324, pp. 1156- 1161 ,(1991) , 10.1056/NEJM199104253241702
William C. Guenther, Richard P. Runyon, Audrey Haber, Fundamentals of Behavioral Statistics. Journal of the American Statistical Association. ,vol. 63, pp. 378- ,(1968) , 10.2307/2283864
Michael K. Brawer, Jeanette Beatie, Mark H. Wener, Robert L. Vessella, Steven D. Preston, Paul H. Lange, Screening for prostatic carcinoma with prostate specific antigen: results of the second year. The Journal of Urology. ,vol. 150, pp. 106- 109 ,(1993) , 10.1016/S0022-5347(17)35409-5