Diagnostic histologique des infections bactériennes nécrosantes extensives du poumon

作者: Sandra Lassalle , Véronique Hofman , Catherine Butori , Dominique Sicard , Paul Hofman

DOI: 10.1016/S0242-6498(05)80143-9

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摘要: Resume Nous rapportons les aspects anatomo-cliniques et histologiques de 4 observations d’infection bacterienne pulmonaire associee a des lesions necrose extensive, dont l’evolution ete foudroyante en quelques heures (2 cas d’infections streptocoque beta hemolytique du groupe A, 1 Staphylococcus aureus un Haemophilus influenzae ). Ces infections bacteriennes necrosantes extensives (IBNE) sont gravissimes compte tenu la production toxines necrosantes. Les stereotypes, combinant une hemorragique extensive diffuse, nappes bacteries reaction inflammatoire cellulaire quasi inexistante. extremement rares elles surviennent sans cause apparente, chez le sujet immunodeficient ou immunocompetent. Elles posent problemes diagnostic differentiel parfois difficile resoudre histologie faisant discuter infection virale associee. Le positif repose sur confontation anatomopathologique microbiologique.

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