Dementia associated with Parkinson’s disease: Applying the Movement Disorder Society Task Force criteria

摘要: Abstract Background Diagnostic criteria and procedures for dementia in Parkinson’s disease (PDD) have been proposed by a Movement Disorders Society Task Force (MDS-TF). The objective of this study was to explore the utility new MDS-TF clinical practice. Methods Two hundred ninety nine PD patients (36.5% with PDD as per MDFS-TF criteria; 33.1% according DSM-IV) were included study. A variety standardized motor, cognitive, psychiatric, global severity measures administered. multivariate logistic regression model built determine variables producing discrepancy between DSM-IV features that distinguished false negative cases. Results Agreement substantial (87.3%; kappa = 0.72), but failed identify 22% fulfilling criteria. False cases older had more severe motor symptoms less psychosis than those true non-demented PD. positives PDD, although difference did not reach statistical significance. Conclusions Our findings suggest are sensitive diagnosis PDD. Old age, absence psychiatric symptoms, impairment can hinder