Acides gras poly-insaturés, phospholipides et fonctions membranaires
作者： A. Grynberg
DOI: 10.1007/978-2-287-33475-7_9
关键词:
摘要: Les acides gras constituent la composante majeure des matieres grasses chez les eucaryotes. Ils se repartissent en trois grands groupes: satures (AGS) sans double liaison, mono-insatures (AGMI) avec une liaison et poly-insatures (AGPI), deux doubles liaisons ou plus. AGS AGMI sont parfois consideres comme denues de specificite fonctionnelle a ľexclusion processus palmitoylation myristoylation, c’est-a-dire covalente ďun (palmitique 16 carbones myristique 14 carbones) sur proteine. Ce biologique ubiquitaire est implique dans nombreuses fonctions membranaires (1). Il n’en va pas meme pour AGPI dont le role fonctionnel specifique important varie (localisation ľenvironnement proteique membranaire, mediateurs intracellulaires signalisation humorale PPARs, messagers intercellulaires prostaglandines leucotrienes, etc.). La plupart tissus humains capables synthetiser partir sucres ďacides amines, car ils possedent Δ9-desaturase.
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