Påverkar EAP sederingsgraden av detomidin hos häst

作者: Frida Karlsson

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摘要: Equine appeasing pheromone (EAP) ar ett feromon som avges vid juveromradet pa ston under digivningsperioden. Detta har framstallts syntetiskt och ingar i produkten ConfidenceEQ gar att kopa receptfritt apotek kliniker. Produkten ska gora hasten avspand fokuserad kan anvandas till exempel inlarning traning samt situationer dar visar tecken oro. Situationer hastagaren sjalv valja anvanda EAP infor transport, veterinarbesok, hovslagarbesok eller tandundersokningar. Ibland detta vara veterinar sedan behover sedera for det ga genomfora vissa undersokningar behandlingar. Det darfor intressant undersoka om paverkar sederingsgraden av detomidin, en vanligt forekommande substans sedering hast. For med detomidin hos hast utfordes trippelblindad, experimentell, prospektiv, crossover-studie 8 hastar ingick. Hastarna behandlades placebo-gel respektive EAP-gel applicerades nedre delen nosborrarna 30 minuter innan 10μg/kg kroppsvikt intravenost. For bedoma hastarna noterades huvudhojd-over-golvet, allman sederingsgrad, separering lappar, kroppshallning, ataxi, reaktion ljud beroring, mekaniska nociceptiva troskelvarden, hjartfrekvens, andningsfrekvens blodtryck. Varden registrerades (baseline) min efter administration EAP, upprepade tillfallen upp 90 givits. Hypotesen var behandlats skulle uppvisa hogre grad langre duration sedering. Ingen statistiskt signifikant skillnad mellan behandling placebo kunde pavisas nagon variablerna. Slutsatsen blir inte sa pass stor utstrackning nagot man ta beaktande nar nyligen sederas detomidin.

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