Topoisomerase-Induced DNA Damage
作者： Yves Pommier , Neil Osheroff
DOI: 10.1007/978-1-4614-0323-4_7
关键词:
摘要: Because of their ability to cleave and religate DNA by covalently bonding one the ends break, topoisomerases are highly susceptible structure. Here, we will review how can damage genome when it contains preexisting lesions at enzyme sites action. This brief chapter gives an overview broad range that lead accumulation cleavage complexes produced I II.
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