MELD Score as a Prognostic Model for Listing Acute Liver Failure Patients for Liver Transplantation

摘要: Abstract Objectives The King’s College Hospital (KCH) criteria are widely used for listing patients with acute liver failure (ALF) transplantation (LT). Recent reports have suggested that the Model End-Stage Liver Disease (MELD) score may be useful in assessing prognosis ALF (nonparacetamol). This study compares prognostic accuracy of two systems paracetamol (POD)-induced treated this unit. Methods Seventy-two (average age 38 years; F:M ratio 2:1) admitted from 1994 to 2005 POD-related were studied. Clinical and biochemical parameters recorded. effect applying a MELD greater than 30 as LT was calculated compared KCH criteria. Outcomes defined LT, death, or full recovery. Results Thirty-one (43%) recovered medical therapy, 29 (40%) died, 12 (17%) underwent LT. Sixty five percent had > therefore could potentially listed on admission; however, using only 24% immediately. Sensitivity negative predictive value higher then KCH; we found much specificity positive value. Conclusion has sensitivity POD-induced However, high false-positive rate associated limits its clinical utility. allow it conjunction avoid unneeded who will likely recover spontaneously.