Multiple segmental spinal cord hypoplasia in a cat.

摘要: Background: The nervous system is one of the most affected by congenital malformations. These can occur during neural tube formation or failed neurogenesis. Segmental spinal cord hypoplasia commonly involves two three segments in thoracolumbar region. It characterized incomplete and may also be followed spine column Clinical signs usually include functional impairment hindlimbs. Diagnosis based on history, clinical signs, age, radiographs confi rmed with necropsy histopathological fi ndings. There no treatment for this condition animals present low life quality. This paper aims to report clinical, radiographic aspects multiple segmental a domestic cat. Case: A 52-days-old, female, Persian breed, cat weighing 0.55 kg was treated presenting history pelvic limb paraplegia associated urinary fecal incontinence since birth. On examination there were fl accid hind limbs absence proprioception, anal refl ex tone postural defi cits. Also, all exes deep superfi cial pain absent. muscular tremors, nystagmus, seizures other central signs. litter showed apparent changes. Radiographic lumbosacral region enlargement canal extending from caudal portion L1 L7 attening dorsal ventral blades. observed that height L5 canal, larger dilatation site, about 300% higher than cranial L1, considered last normal segment. Due quality, animal euthanized samples collected. Histopathological neuronal loss gray matter, thickening dura mater nition white rming diagnosis regions cord. Discussion: Based reported, had lower motor neuron lesion, nerve conduction femoral, sciatic, pudendal nerves, afferent sensory bers brain. medullary measurement model proposed useful quantifying, need advanced imaging, which currently an empirical subjective evaluation. prognosis reserved, considering specifi c correction Few reports show follow-up after cases euthanasia indicated due weakness Intestinal infections are common, besides appearance scars because paraplegic members dragging. disease rarely reported veterinary medical literature pets many features remain unknown. In case, data obtained physical corroborated signifi cantly suspicious disease. sign lumbar vertebrae strongly suggestive abnormalities. quality prognosis, euthanized, allowing post-mortem hypoplasia.