A snapshot of antimicrobial resistance in Mexico. Results from 47 centers from 20 states during a six-month period

作者: Elvira Garza-González , Rayo Morfín-Otero , Soraya Mendoza-Olazarán , Paola Bocanegra-Ibarias , Samantha Flores-Treviño

DOI: 10.1371/JOURNAL.PONE.0209865

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摘要: Aim We aimed to assess the resistance rates of antimicrobial-resistant, in bacterial pathogens epidemiological importance 47 Mexican centers. Material and methods In this retrospective study, we included a stratified sample centers, covering 20 states. Selected isolates considered as potential causatives disease collected over 6-month period were included. Laboratories employed their usual perform microbiological studies. The results deposited into database analyzed with WHONET 5.6 software. Results total 22,943 strains Regarding Gram-negatives, carbapenem was detected ≤ 3% Escherichia coli, 12.5% Klebsiella sp. Enterobacter sp., up 40% Pseudomonas aeruginosa; latter, rate for piperacillin-tazobactam (TZP) high 19.1%. In Acinetobacter cefepime, ciprofloxacin, meropenem, TZP higher than 50%. Gram-positives, methicillin Staphylococcus aureus (MRSA) 21.4%, vancomycin (VAN) reached 21% Enterococcus faecium. presented highest multidrug (53%) followed by (22.6%) E. coli (19.4%). Conclusion The specific groups enterobacteria deserve special attention Mexico. Vancomycin-resistant enterococci (VRE) MRSA are common our hospitals. Our present valuable information implementation measures control drug resistance.

参考文章(32)
Juan L. Mosqueda-Gómez, Aldo Montaño-Loza, Ana L. Rolón, Carlos Cervantes, J. Miriam Bobadilla-del-Valle, Jesús Silva-Sánchez, Ulises Garza-Ramos, Angelina Villasís-Keever, Arturo Galindo-Fraga, Guillermo M. Ruiz Palacios, Alfredo Ponce-de-León, José Sifuentes-Osornio, Molecular epidemiology and risk factors of bloodstream infections caused by extended-spectrum β-lactamase-producing Klebsiella pneumoniae ☆: A case–control study International Journal of Infectious Diseases. ,vol. 12, pp. 653- 659 ,(2008) , 10.1016/J.IJID.2008.03.008
J. Silva, C. Aguilar, M.A. Estrada, G. Echániz, N. Carnalla, A. Soto, F.J. López-Antuñano, Susceptibility to New β-Lactams of Enterobacterial Extended-Spectrum β-Lactamase (ESBL) Producers and Penicillin-Resistant Streptococcus pneumoniae in Mexico Journal of Chemotherapy. ,vol. 10, pp. 102- 107 ,(1998) , 10.1179/JOC.1998.10.2.102
Rayo Morfin-Otero, Juan Carlos Tinoco-Favila, Helio S Sader, Lorena Salcido-Gutierrez, Hector Raul Perez-Gomez, Esteban Gonzalez-Diaz, Luis Petersen, Eduardo Rodriguez-Noriega, Resistance trends in gram-negative bacteria: surveillance results from two Mexican hospitals, 2005–2010 BMC Research Notes. ,vol. 5, pp. 277- 277 ,(2012) , 10.1186/1756-0500-5-277
Rayo Morfin-Otero, Eduardo Rodriguez-Noriega, Lalitagauri M. Deshpande, Helio S. Sader, Mariana Castanheira, Dissemination of a blaVIM-2-Carrying Integron Among Enterobacteriaceae Species in Mexico: Report from the SENTRY Antimicrobial Surveillance Program Microbial Drug Resistance. ,vol. 15, pp. 33- 35 ,(2009) , 10.1089/MDR.2009.0878
Fernando Reyna-Flores, Humberto Barrios, Ulises Garza-Ramos, Alejandro Sánchez-Pérez, Teresa Rojas-Moreno, Felipe J. Uribe-Salas, Reynero Fagundo-Sierra, Jesus Silva-Sanchez, Molecular epidemiology of Escherichia coli O25b-ST131 isolates causing community-acquired UTIs in Mexico. Diagnostic Microbiology and Infectious Disease. ,vol. 76, pp. 396- 398 ,(2013) , 10.1016/J.DIAGMICROBIO.2013.03.026
I.M. Gould, The epidemiology of antibiotic resistance International Journal of Antimicrobial Agents. ,vol. 32, pp. S2- S9 ,(2008) , 10.1016/J.IJANTIMICAG.2008.06.016
Rayo Morfín-Otero, Soraya Mendoza-Olazarán, Jesús Silva-Sánchez, Eduardo Rodríguez-Noriega, Jorge Laca-Díaz, Perla Tinoco-Carrillo, Luis Petersen, Perla López, Fernando Reyna-Flores, Dolores Alcantar-Curiel, Ulises Garza-Ramos, Elvira Garza-González, Characterization of Enterobacteriaceae Isolates Obtained from a Tertiary Care Hospital in Mexico, Which Produces Extended-Spectrum β-Lactamase Microbial Drug Resistance. ,vol. 19, pp. 378- 383 ,(2013) , 10.1089/MDR.2012.0263
Thomas G Slama, Gram-negative antibiotic resistance: there is a price to pay Critical Care. ,vol. 12, pp. 1- 7 ,(2008) , 10.1186/CC6820
María Dolores Alcántar-Curiel, Luis Francisco García-Torres, María Inés González-Chávez, Rayo Morfín-Otero, Catalina Gayosso-Vázquez, Ma. Dolores Jarillo-Quijada, José Luis Fernández-Vázquez, Silvia Giono-Cerezo, Eduardo Rodríguez-Noriega, José Ignacio Santos-Preciado, Molecular mechanisms associated with nosocomial carbapenem-resistant Acinetobacter baumannii in Mexico. Archives of Medical Research. ,vol. 45, pp. 553- 560 ,(2014) , 10.1016/J.ARCMED.2014.10.006
Anjali N. Kunz, Itzhak Brook, Emerging resistant Gram-negative aerobic bacilli in hospital-acquired infections. Chemotherapy. ,vol. 56, pp. 492- 500 ,(2010) , 10.1159/000321018