A phase I trial of weekly gemcitabine and subcutaneous interferon alpha in patients with refractory renal cell carcinoma.

作者: F. Perez-Zincer , T. Olencki , G.T. Budd , D. Peereboom , P. Elson

DOI: 10.1023/A:1016214030069

关键词:

摘要: Introduction: Recombinant humaninterferon-α2b (rHuIFN-α2b)and Interleukin-2 have limitedeffectiveness in the treatment ofmetastatic renal cell carcinoma (MRCC).Gemcitabine (Gemzar®) is also reported tohave activity against MRCC, and recent invitro, nude mice xenografts, humandata suggests increased ofgemcitabine when combined withIFN-α2b.

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