Bullatalicin, a novel bioactive acetogenin from Annona bullata (Annonaceae)
作者： Yu-hua Hui , J.Kent Rupprecht , Jon E. Anderson , Ya-mei Liu , David L. Smith
DOI: 10.1016/S0040-4020(01)89160-2
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摘要: Abstract Bullatalicin, a novel bioactive acetogenin having two nonadjacent tetrahydrofuran rings, has been isolated from the bark of Annona bullata (Annonaceae). Its structure elecidated chemical and spectral data. This compound showed potent selective cytotoxic activities for certain human tumor cell lines with ED50 values as low 10−7 mcg/ml.
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