A model for lymphatic regeneration in tissue repair of the intestinal muscle coat.
作者： Hiroshi Shimoda , Seiji Kato
DOI: 10.1016/S0074-7696(06)50003-8
关键词:
摘要: The gastrointestinal lymphatic system, which comprises a network of thin-walled vessels, is essential for the regulation tissue fluid volume, immune function, and transport fatty nutrients. identification specific endothelial markers has facilitated analyses organization lymphangiogenesis during individual development repair. intestinal muscle coat producing motor activity develops dense maze-like by vascular sprouting consisting thin projections splitting vessels. regeneration in repair essentially attributable to from preexisting lymphatics, it progresses vigorously with maturation. regrowing cells exhibit structural changes indicating high migratory potential close association regenerating stromal cells. upregulation VEGF-C, lymphangiogenic molecule, subpopulation probably contributes activating its receptor, VEGFR-3, on
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