Synthesis and evaluation of amides surrogates of dopamine D3 receptor ligands.
作者： Mickaël Jean , Jacques Renault , Nicolas Levoin , Denis Danvy , Thierry Calmels
DOI: 10.1016/J.BMCL.2010.07.096
关键词:
摘要: Isosteric replacement of the amide function and modulation arylpiperazine moiety known dopamine D3 receptor ligands led to potent selective compounds. Enhanced bioavailability preferential brain distribution make compound 6c a good candidate for pharmacological clinical evaluation.
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sci-hub.se 参考文章(19)
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