Relationship between antimicrobial resistance and class I integron in Pseudomonas aeruginosa isolated from clinical specimens in Yazd during 2012-2013

作者: Hengameh Zandi , Hasan Kosha , Fatemeh Akhavan , Mohadeseh Zarei-Yazdeli , Gilda Eslami

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摘要: Background: Antimicrobial resistance in Pseudomonas aeruginosa has been increasing recent years. The aim of this study was to investigate the relationship between antimicrobial and class I integron P. isolated from clinical specimens Yazd city. Materials Methods: This cross-sectional carried out on 144 strains April 2012 2013. All samples were initially identified by biochemical method antibiotic test performed using disc diffusion according CLSI recommendations. PCR for detection integron. Results: Seventy-nine (54.9%) patients male with mean age 34.9+22.7 Resistance rates various antibiotics as follows: gentamicin (63.2%), imipenem (62.5%), amikacin (58.3%), ceftazidime (56.9%), ticarcillin (55.6%), tobramycin piperacillin ciprofloxacin (48.6%) 75.3% isolates detected multi-drug resistant. results showed that 119 (82.6%) Conclusion: Class integrons are commonly found samples. Therefore, transfer genes is often related these contribution should be evaluated.

参考文章(32)
Po-Ren Hsueh, Lee-Jene Teng, Pan-Chyr Yang, Yu-Chi Chen, Shen-Wu Ho, Kwen-Tay Luh, Persistence of a multidrug-resistant Pseudomonas aeruginosa clone in an intensive care burn unit. Journal of Clinical Microbiology. ,vol. 36, pp. 1347- 1351 ,(1998) , 10.1128/JCM.36.5.1347-1351.1998
Kanchana Poonsuk, Chanwit Tribuddharat, Rungtip Chuanchuen, Aminoglycoside resistance mechanisms in Pseudomonas aeruginosa isolates from non-cystic fibrosis patients in Thailand. Canadian Journal of Microbiology. ,vol. 59, pp. 51- 56 ,(2013) , 10.1139/CJM-2012-0465
Alessandra Carattoli, IMPORTANCE OF INTEGRONS IN THE DIFFUSION OF RESISTANCE Veterinary Research. ,vol. 32, pp. 243- 259 ,(2001) , 10.1051/VETRES:2001122
Maria Renata Gomes Franco, Hélio Hehl Caiaffa-Filho, Marcelo Nascimento Burattini, Flávia Rossi, Metallo-beta-lactamases among imipenem-resistant Pseudomonas aeruginosa in a Brazilian university hospital Clinics. ,vol. 65, pp. 825- 829 ,(2010) , 10.1590/S1807-59322010000900002
Aaron M. Wendelboe, Joan Baumbach, David B. Blossom, Patricia Frank, Arjun Srinivasan, C. Mack Sewell, Outbreak of Cystoscopy Related Infections With Pseudomonas Aeruginosa: New Mexico, 2007 Journal of Urology. ,vol. 180, pp. 588- 592 ,(2008) , 10.1016/J.JURO.2008.04.003
Richard I. Jaffe, Janae D. Lane, Christopher W. Bates, Real-time identification of Pseudomonas aeruginosa direct from clinical samples using a rapid extraction method and polymerase chain reaction (PCR) Journal of Clinical Laboratory Analysis. ,vol. 15, pp. 131- 137 ,(2001) , 10.1002/JCLA.1016
Célia Maria Carvalho Pereira Araujo Romão, Yaisa Naziozeno de Faria, Luciana Roberto Pereira, Marise Dutra Asensi, Susceptibility of clinical isolates of multiresistant Pseudomonas aeruginosa to a hospital disinfectant and molecular typing Memorias Do Instituto Oswaldo Cruz. ,vol. 100, pp. 541- 548 ,(2005) , 10.1590/S0074-02762005000500015
Masaru Ohara, Shuntaro Kouda, Makoto Onodera, Yoshihiro Fujiue, Megumi Sasaki, Tadahiro Kohara, Seiya Kashiyama, Shizue Hayashida, Manami Kadono, Hitoshi Komatsuzawa, Naomasa Gotoh, Tuguru Usui, Hideyuki Itaha, Masao Kuwabara, Takashi Yokoyama, Motoyuki Sugai, Molecular Characterization of Imipenem-ResistantPseudomonas aeruginosain Hiroshima, Japan Microbiology and Immunology. ,vol. 51, pp. 271- 277 ,(2007) , 10.1111/J.1348-0421.2007.TB03908.X
Berna Özbek, AA Gerceker, In-vitro activities of various antibiotics, alone and in combination with amikacin against Pseudomonas aeruginosa. International Journal of Antimicrobial Agents. ,vol. 18, pp. 567- 570 ,(2001) , 10.1016/S0924-8579(01)00458-7